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System NAD+ at a Glance
| Our Rating | 4.7 / 5 |
|---|---|
| Best For | Choosing injection or nasal, priced separately |
| Injection | From $89 first month |
| Nasal Spray | From $69 first month |
| Process | Fully online |
| Ongoing Price | Shown during intake |
| Medication Type | Compounded NAD+ (not FDA-approved) |
What Is System NAD+?
System is an online health brand that sells NAD+ in two formats and, unusually, prices them separately. Injectable NAD+ starts at $89 for the first month and nasal NAD+ at $69, so you can choose based on both comfort and budget instead of being steered toward one product.
Being able to compare formats side by side is helpful because they are not equivalent. Injections deliver NAD+ under the skin and absorb more completely; nasal sprays avoid needles but absorb less. Having both at visible prices lets you make that trade-off knowingly.
The whole process runs online. System shows first-month pricing upfront, while ongoing monthly pricing appears during intake — something to check before you commit. As with every provider here, the medication is compounded, and the FDA’s guidance on compounding is clear that such drugs are not FDA-approved.
Low introductory prices make System appealing for a first experiment with NAD+. If you are unsure whether you will tolerate injections, starting on the cheaper nasal spray is a low-cost way to find out whether NAD+ suits you at all.
The main homework is to compare the renewal price shown during intake with other providers, since that is what you will pay from month two onward.
System ranks fifth in our best NAD+ providers list. It does the basics well, but the providers above it publish more about renewal pricing, guarantees and pharmacy testing, which is why it sits just outside the top four.
Pros & Cons
Pros
- Both injection and nasal NAD+ options
- Accessible first-month pricing
- Fully online process
Cons
- Compounded NAD+ — not an FDA-approved finished drug product
- Ongoing pricing shown during intake
How System NAD+ Works
Pick a format
Compare the injection and nasal first-month prices and choose one.
Online intake
Complete a health questionnaire for clinician review.
See ongoing pricing
Your renewal price appears during intake — note it before checking out.
Delivery
Approved orders ship to your home.
Safety & What to Know
The two formats carry different side-effect profiles. Injections can cause injection-site soreness or redness; the nasal spray may irritate the nose or cause sneezing. Flushing, nausea and headaches have been reported with both. Start with the dose prescribed and do not double up if you miss one.
Disclose medications and conditions honestly during intake. NAD+ is not well studied in pregnancy, breastfeeding or people with serious chronic illness, so expect a cautious response from the reviewing clinician in those situations.
System NAD+ Pricing
| Injection | From $89 (first month) |
|---|---|
| Nasal Spray | From $69 (first month) |
| Renewal | Shown during intake |
| Process | Online |
The low first-month prices make System an inexpensive way to try NAD+, but they are introductory. Write down the ongoing rate shown in intake so you can compare total cost with other providers.
Who System NAD+ Is For
A good fit if you
- Want to choose between injection and nasal
- Like seeing each format’s price separately
- Want a low-cost first month
- Prefer a fully online process
Look elsewhere if you
- Want ongoing pricing published before intake
- Need extensive provider support
- Want a money-back guarantee
How System NAD+ Compares
BettermeRx offers injection or nasal spray from $99 a month with a refund guarantee. He & She MD prices injection, cream and nasal spray identically at $149 a month. System is the middle ground for people who want both injection and nasal priced separately in the open. Our NAD+ provider guide compares them all.
Frequently Asked Questions
Our Verdict
★ 4.7 out of 5
System is a sensible starting point for anyone undecided between injections and nasal spray, with separate, low first-month prices for each. Check the renewal price during intake; if it fits your budget, System is a straightforward way to try NAD+.
See the full Best NAD+ Therapy Providers ranking →
Reviewed by
Dr. Lisa ChenHealth & Wellness Editor
Dr. Lisa Chen holds a Doctor of Pharmacy (PharmD) from UCSF and has 8 years of clinical experience in patient care and health education. She specializes in reviewing digital health platforms, wellness products, and nutrition services. Dr. Chen consults with a panel of MDs and registered dietitians to ensure all health content meets clinical accuracy standards.